Details for gene set KEGG_NEUROACTIVE_LIGAND_RECEPTOR

Table: GSEA Results Summary

Dataset	RNR_GSEA_DESEQ2_FC
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION
Enrichment Score (ES)	-0.19092007
Normalized Enrichment Score (NES)	-3.5698352
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CGA	37	3.339	0.0018	No
2	PRSS1	47	2.924	0.0051	No
3	OPRD1	66	2.581	0.0079	No
4	GABRA1	87	2.226	0.0106	No
5	GCGR	93	2.179	0.0141	No
6	GABRQ	125	1.952	0.0162	No
7	GRM5	156	1.783	0.0183	No
8	F2RL3	164	1.710	0.0218	No
9	SSTR4	172	1.642	0.0252	No
10	HTR2A	241	1.367	0.0252	No
11	CHRNB3	268	1.286	0.0276	No
12	CCKBR	274	1.281	0.0311	No
13	CHRNA9	286	1.250	0.0343	No
14	CHRNA6	303	1.200	0.0372	No
15	MCHR2	343	1.116	0.0389	No
16	AGTR2	384	1.041	0.0405	No
17	NMBR	392	1.026	0.0439	No
18	MTNR1A	398	1.015	0.0474	No
19	MTNR1B	414	1.008	0.0504	No
20	GRM1	470	0.943	0.0512	No
21	RXFP2	490	0.917	0.0540	No
22	GALR1	513	0.878	0.0565	No
23	PTH2R	515	0.874	0.0603	No
24	GABRG1	533	0.850	0.0631	No
25	CHRM3	535	0.848	0.0669	No
26	SSTR3	579	0.791	0.0683	No
27	GRIK2	616	0.756	0.0701	No
28	GRIA3	629	0.745	0.0733	No
29	NPY5R	641	0.734	0.0765	No
30	HTR2B	649	0.728	0.0799	No
31	NPY1R	670	0.710	0.0826	No
32	CHRNE	684	0.697	0.0857	No
33	GLRA1	717	0.667	0.0877	No
34	GABRB1	772	0.623	0.0886	No
35	GRM8	778	0.623	0.0921	No
36	GABRA2	825	0.609	0.0934	No
37	GABRA4	858	0.589	0.0954	No
38	LPAR4	880	0.574	0.0980	No
39	GLRA2	898	0.570	0.1009	No
40	GALR3	910	0.567	0.1041	No
41	RXFP1	920	0.561	0.1074	No
42	ADRB3	923	0.559	0.1111	No
43	DRD1	924	0.558	0.1149	No
44	KISS1R	950	0.546	0.1173	No
45	FSHB	1020	0.508	0.1173	No
46	CALCR	1066	0.494	0.1187	No
47	F2RL1	1257	0.421	0.1121	No
48	CHRNA7	1298	0.405	0.1137	No
49	HTR1D	1309	0.401	0.1170	No
50	TRPV1	1413	0.367	0.1151	No
51	GRIN1	1451	0.356	0.1169	No
52	HTR1E	1492	0.349	0.1185	No
53	PRLR	1504	0.348	0.1217	No
54	CYSLTR2	1648	0.320	0.1177	No
55	HTR7	1654	0.318	0.1212	No
56	GLP1R	1656	0.318	0.1250	No
57	THRB	1705	0.310	0.1261	No
58	HRH4	1725	0.307	0.1289	No
59	GABRR1	1737	0.304	0.1321	No
60	GPR83	1851	0.285	0.1297	No
61	GABRB3	1910	0.273	0.1303	No
62	P2RX1	1996	0.262	0.1295	No
63	UTS2R	2074	0.254	0.1291	No
64	GRIN2A	2109	0.250	0.1310	No
65	GHRHR	2145	0.246	0.1329	No
66	S1PR1	2153	0.245	0.1363	No
67	LEPR	2167	0.243	0.1394	No
68	P2RY13	2193	0.240	0.1418	No
69	P2RY8	2233	0.236	0.1435	No
70	MAS1	2269	0.231	0.1454	No
71	P2RY14	2272	0.231	0.1491	No
72	GABRB2	2287	0.229	0.1521	No
73	S1PR5	2426	0.215	0.1484	No
74	FSHR	2477	0.211	0.1494	No
75	PRLHR	2503	0.210	0.1518	No
76	S1PR2	2591	0.203	0.1509	No
77	GRIN3A	2605	0.202	0.1540	No
78	F2	2682	0.195	0.1536	No
79	GRIK4	2687	0.194	0.1572	No
80	PRSS3	2936	0.176	0.1475	No
81	CHRM2	2981	0.174	0.1489	No
82	P2RX4	3110	0.166	0.1457	No
83	VIPR2	3192	0.160	0.1451	No
84	GABRA3	3303	0.155	0.1429	No
85	FPR3	3403	0.150	0.1413	No
86	HCRTR1	3447	0.148	0.1427	No
87	P2RY4	3560	0.142	0.1404	No
88	HTR4	3825	0.129	0.1298	No
89	GABRG2	3891	0.127	0.1301	No
90	F2R	3970	0.124	0.1296	No
91	NR3C1	4151	0.117	0.1236	No
92	P2RY1	4196	0.115	0.1250	No
93	P2RX3	4450	0.106	0.1150	No
94	LHB	4534	0.103	0.1143	No
95	CNR2	4697	0.098	0.1092	No
96	GABRP	4861	0.092	0.1041	No
97	CTSG	4891	0.092	0.1064	No
98	HRH2	5735	0.069	0.0642	No
99	AVPR1A	5904	0.064	0.0589	No
100	GRIA1	6038	0.061	0.0554	No
101	EDNRA	6041	0.061	0.0591	No
102	GLRB	6295	0.055	0.0491	No
103	CHRNA5	6729	0.045	0.0293	No
104	GRPR	6947	0.041	0.0213	No
105	GABBR1	7283	0.034	0.0069	No
106	GABRE	7435	0.030	0.0024	No
107	ADORA2B	7487	0.029	0.0034	No
108	P2RY2	7524	0.028	0.0053	No
109	CHRNA2	7671	0.025	0.0011	No
110	HTR1B	7869	0.022	-0.0058	No
111	DRD2	7972	0.020	-0.0076	No
112	GRIA4	8192	0.015	-0.0157	No
113	DRD4	8250	0.014	-0.0150	No
114	EDNRB	8261	0.014	-0.0118	No
115	SCTR	9051	-0.002	-0.0510	No
116	C3AR1	9063	-0.002	-0.0478	No
117	GHR	9188	-0.005	-0.0507	No
118	GH1	9261	-0.006	-0.0509	No
119	CHRNA1	9861	-0.018	-0.0797	No
120	PTGIR	10040	-0.021	-0.0856	No
121	GRIK1	10239	-0.025	-0.0926	No
122	C5AR1	10286	-0.026	-0.0913	No
123	LPAR6	10437	-0.029	-0.0957	No
124	MLNR	10637	-0.033	-0.1027	No
125	HRH1	10734	-0.035	-0.1042	No
126	GRM2	10857	-0.038	-0.1070	No
127	VIPR1	10969	-0.041	-0.1093	No
128	MC1R	11228	-0.047	-0.1196	No
129	GRID1	11549	-0.054	-0.1332	No
130	GRIK3	11879	-0.062	-0.1473	No
131	ADORA3	12298	-0.072	-0.1663	No
132	AVPR2	12302	-0.072	-0.1627	No
133	TACR2	12504	-0.078	-0.1698	No
134	ADRA1B	12594	-0.080	-0.1709	No
135	TBXA2R	12664	-0.082	-0.1708	No
136	LTB4R2	12821	-0.087	-0.1755	No
137	TSPO	12900	-0.089	-0.1760	No
138	PARD3	13008	-0.092	-0.1780	No
139	PLG	13024	-0.093	-0.1751	No
140	SSTR1	13028	-0.093	-0.1714	No
141	GABRD	13052	-0.094	-0.1689	No
142	ADRB2	13083	-0.094	-0.1668	No
143	THRA	13113	-0.095	-0.1645	No
144	GRIN3B	13244	-0.100	-0.1678	No
145	GABRA6	13289	-0.101	-0.1664	No
146	P2RX7	13301	-0.102	-0.1633	No
147	CCKAR	13360	-0.104	-0.1626	No
148	PTGER4	13389	-0.105	-0.1604	No
149	LPAR1	13494	-0.108	-0.1622	No
150	GIPR	13604	-0.112	-0.1644	No
151	NMUR1	13663	-0.114	-0.1638	No
152	CHRNB1	13697	-0.115	-0.1618	No
153	P2RY6	13923	-0.125	-0.1702	No
154	CALCRL	13989	-0.128	-0.1700	No
155	GRM3	14032	-0.130	-0.1685	No
156	CRHR2	14080	-0.132	-0.1672	No
157	OXTR	14332	-0.146	-0.1771	No
158	TACR3	14337	-0.146	-0.1736	No
159	LPAR2	14657	-0.161	-0.1871	Yes
160	GRIN2D	14720	-0.165	-0.1867	Yes
161	CHRNB2	14798	-0.171	-0.1871	Yes
162	PTGFR	14838	-0.174	-0.1855	Yes
163	LPAR3	14884	-0.177	-0.1841	Yes
164	P2RY10	14921	-0.180	-0.1823	Yes
165	OPRL1	14942	-0.181	-0.1796	Yes
166	ADORA2A	15000	-0.185	-0.1789	Yes
167	AGTR1	15193	-0.200	-0.1856	Yes
168	CYSLTR1	15205	-0.201	-0.1824	Yes
169	ADRA2C	15245	-0.204	-0.1807	Yes
170	CHRM1	15266	-0.206	-0.1780	Yes
171	PTH1R	15314	-0.210	-0.1768	Yes
172	CHRM5	15320	-0.211	-0.1733	Yes
173	PTGDR	15408	-0.219	-0.1742	Yes
174	GRM6	15452	-0.222	-0.1728	Yes
175	S1PR3	15492	-0.227	-0.1711	Yes
176	P2RY11	15504	-0.228	-0.1679	Yes
177	LTB4R	15563	-0.233	-0.1673	Yes
178	CHRNA10	15683	-0.247	-0.1700	Yes
179	HTR1F	15742	-0.255	-0.1694	Yes
180	NTSR2	15773	-0.259	-0.1672	Yes
181	NPFFR2	15784	-0.261	-0.1640	Yes
182	LHCGR	15805	-0.264	-0.1613	Yes
183	GNRHR	15835	-0.268	-0.1591	Yes
184	HCRTR2	15851	-0.269	-0.1561	Yes
185	P2RX5	15869	-0.271	-0.1532	Yes
186	ADRB1	15883	-0.273	-0.1501	Yes
187	ADRA1A	15890	-0.274	-0.1467	Yes
188	APLNR	15965	-0.283	-0.1469	Yes
189	GZMA	15987	-0.286	-0.1443	Yes
190	ADRA2B	15993	-0.287	-0.1408	Yes
191	PTAFR	15996	-0.287	-0.1371	Yes
192	F2RL2	16017	-0.290	-0.1344	Yes
193	CHRNG	16140	-0.307	-0.1372	Yes
194	PTGER2	16220	-0.322	-0.1377	Yes
195	TSHR	16242	-0.326	-0.1351	Yes
196	GRIN2C	16250	-0.326	-0.1317	Yes
197	S1PR4	16446	-0.365	-0.1385	Yes
198	ADORA1	16452	-0.366	-0.1350	Yes
199	MC5R	16498	-0.377	-0.1337	Yes
200	GALR2	16500	-0.377	-0.1299	Yes
201	GPR35	16507	-0.378	-0.1265	Yes
202	MC4R	16517	-0.380	-0.1232	Yes
203	FPR2	16549	-0.387	-0.1211	Yes
204	GLP2R	16676	-0.419	-0.1242	Yes
205	NPFFR1	16681	-0.421	-0.1206	Yes
206	GABRR2	16714	-0.430	-0.1185	Yes
207	PTGER3	16718	-0.431	-0.1149	Yes
208	MCHR1	16745	-0.436	-0.1125	Yes
209	OPRM1	16799	-0.453	-0.1116	Yes
210	ADRA1D	16824	-0.461	-0.1092	Yes
211	NTSR1	16833	-0.464	-0.1058	Yes
212	NMUR2	16900	-0.480	-0.1056	Yes
213	ADCYAP1R1	16959	-0.493	-0.1050	Yes
214	GPR156	16980	-0.499	-0.1023	Yes
215	P2RX6	16986	-0.500	-0.0988	Yes
216	PRL	17016	-0.506	-0.0966	Yes
217	SSTR2	17118	-0.542	-0.0983	Yes
218	GRIK5	17148	-0.555	-0.0961	Yes
219	GRIA2	17150	-0.556	-0.0923	Yes
220	HRH3	17186	-0.572	-0.0904	Yes
221	ADRA2A	17190	-0.575	-0.0868	Yes
222	NPBWR1	17252	-0.603	-0.0864	Yes
223	PTGER1	17292	-0.625	-0.0847	Yes
224	SSTR5	17301	-0.629	-0.0813	Yes
225	CNR1	17364	-0.661	-0.0809	Yes
226	GRID2	17382	-0.669	-0.0781	Yes
227	CHRNA3	17435	-0.696	-0.0771	Yes
228	CHRM4	17448	-0.703	-0.0740	Yes
229	GABBR2	17458	-0.711	-0.0707	Yes
230	TSHB	17474	-0.720	-0.0677	Yes
231	FPR1	17496	-0.733	-0.0651	Yes
232	HTR6	17531	-0.751	-0.0631	Yes
233	NPY2R	17535	-0.755	-0.0595	Yes
234	BRS3	17566	-0.778	-0.0573	Yes
235	GRM4	17584	-0.793	-0.0545	Yes
236	DRD5	17619	-0.823	-0.0525	Yes
237	OPRK1	17632	-0.832	-0.0494	Yes
238	CRHR1	17641	-0.840	-0.0461	Yes
239	CHRND	17647	-0.842	-0.0425	Yes
240	DRD3	17661	-0.852	-0.0395	Yes
241	TRHR	17681	-0.870	-0.0367	Yes
242	TACR1	17708	-0.891	-0.0343	Yes
243	BDKRB1	17835	-0.987	-0.0374	Yes
244	HTR2C	17850	-0.995	-0.0344	Yes
245	GH2	17913	-1.052	-0.0340	Yes
246	MC3R	17929	-1.072	-0.0310	Yes
247	TAAR6	17954	-1.090	-0.0285	Yes
248	LEP	17975	-1.102	-0.0258	Yes
249	BDKRB2	17981	-1.110	-0.0223	Yes
250	GRIN2B	18050	-1.185	-0.0222	Yes
251	GABRA5	18063	-1.201	-0.0191	Yes
252	CHRNB4	18099	-1.237	-0.0172	Yes
253	HTR1A	18127	-1.294	-0.0149	Yes
254	GRM7	18130	-1.297	-0.0112	Yes
255	GHSR	18156	-1.347	-0.0088	Yes
256	CHRNA4	18169	-1.385	-0.0056	Yes
257	TAAR5	18200	-1.443	-0.0035	Yes
258	GLRA3	18344	-1.738	-0.0075	Yes
259	AVPR1B	18370	-1.854	-0.0051	Yes
260	P2RX2	18385	-1.915	-0.0020	Yes
261	MC2R	18444	-2.148	-0.0014	Yes
262	GABRG3	18495	-2.639	-0.0003	Yes
263	GPR50	18539	-3.606	0.0011	Yes
264	TAAR1	18614	-17.501	0.0009	Yes